INCREASED ZINC AND MANGANESE IN PARALLEL WITH NEURODEGENERATION, SYNAPTIC PROTEIN CHANGES AND ACTIVATION OF AKT/GSK3 SIGNALING IN OVINE CLN6 NEURONAL CEROID LIPOFUSCINOSIS.

Increased zinc and manganese in parallel with neurodegeneration, synaptic protein changes and activation of Akt/GSK3 signaling in ovine CLN6 neuronal ceroid lipofuscinosis.

Mutations in the CLN6 gene cause a variant late infantile form of neuronal ceroid lipofuscinosis (NCL; Batten disease).CLN6 loss leads to disease clinically characterized by vision impairment, motor and cognitive dysfunction, and seizures.Accumulating evidence suggests that alterations in metal homeostasis and cellular signaling pathways are implic

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Recent advances in antimicrobial air filter

The worsening air quality has become an environmental issue since it has a serious effect on human health.This is generally attributed to airborne particles including various pathogens and others fine particles.Even though air filters show excellent removal efficiency towards pathogens, the captured microorganism can remain viable in the filter, gr

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Comparison of the physiological properties of human periodontal-masseteric reflex evoked by incisor and canine stimulation

Introduction: The present study was designed to clarify whether the bilateral cooperation in the human periodontal-masseteric reflex (PMR) differs between central incisors and canines.Methods: Surface array electrodes were placed on the bilateral masseter muscles to simultaneously record the firing activities of Care Kit single motor units from bot

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The Power of Belief: How Ethnocentrism, Religion, and Brand Importance Shape Boycott Behavior and Brand Perceptions in Indonesia

Purpose: This study aims to understand the role of boycott intention in mediating the effects of consumer ethnocentrism, religious animosity, legitimacy, and brand importance on brand image, loyalty, and product judgment among Starbucks consumers in Indonesia.Method: This study was conducted using quantitative methods to test the proposed theoretic

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